Aside from this paper's inclusion in the NEJM's section on healthcare
reform (U.S.), the concerns are and have been a constant. Numerous
recent literature reviews on QOL indices confirm these gaps. Selected
Cochrane Collaboration reviews also note shortfalls in the reporting of
side effects, symptoms and QOL in clinical trials.
Sandi
http://healthcarereform.nejm.org/?p=3140&query=home
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