Lin's very helpful note prompted a quick inspection of my copy, which is not annotated or marked in the text proper, other than a bookbinder's code mark in the gutter of leaf B1r. I skimmed the book again, looking for any marks, sneezum, tobacco leavings, or folded down pages, and found nothing. But this book was issued uncut, unopened, and every single leaf in Twain's copy was opened. While some other member of the family could have opened and read the pages, it's worth noting that (usually) Twain did not bother to open leaves that he didn't want to read, as evidenced by more than a few books from his library were a portion of a book was opened and even marked, while the rest of the book was left unopened. The book does show moderate use from handling, which is significant because it was handled very little after it was sold to Estelle Doheny in 1940 by Max Hunley, a dealer who was acquiring things from Clara at the time. Kevin Mac Donnell Austin TX