Sam's first sojourn away from home included a leg from Chicago, Illinois 
to Monroe, Michigan, where he took a steamer across Lake Erie.  All the 
references I've found regarding this trip have said he traveled first to 
Toledo and then Monroe.  I've not seen any corroborating evidence from 
Twain and my study of the railroads of that time suggest he traveled 
straight through Adrian and into Monroe on the Michigan Southern and 
Northern Indiana Rail Road. There was no reason for him to detour to 
Toledo. This line would later become the Lake Shore and Michigan 
Southern Railway.